Kathryn Watt


I am a post-graduate research assistant working on a BBSRC-funded project entitled early-life effects on ageing in an evolutionary context: This project principally focuses on the long-term study of Soay sheep on St Kilda. My work involves developing and validating assays to measure variation in key physiological parameters associated with immunity and ageing, using biological samples collected from free-living mammals. The aim is to understand how genes and early-life environmental conditions interact to influence an organism's life history and physiological function right across the adult lifespan under natural conditions.
 
Publications (previously Kathryn Lamza):  

Watt, K.; Nussey, D.H.; Maclellan, R.; Pilkington, J.G.; Pemberton, J.M.; McNeilly, T.N. (2016) Faecal antibody levels as a non-invasive method for measuring immunity to gastro-intestinal nematodes in ecological studies. Ecology & Evolution; on-line early.

Handel, I.; Watt, K.A.; Pilkington, J.G.; Pemberton, J.M.; Macrae, A.; Scott, P.; McNeilly, T.N.; Berry, J.L.; Clements, D.N.; Nussey, D.H.; Mellanby, R.J. (2016) Vitamin D status predicts reproductive fitness in a wild sheep population. Scientific Reports. 6:18986.

Arthur, C.; Watt, K.; Nussey, D.H.; Pemberton, J.M.; Pilkington, J.G.; Herman, J.S.; Timmons, Z.L.; Clements, D.N.; Scott, P.R. (2015) Osteoarthritis of the temporo-mandibular joint in free-living Soay sheep on St Kilda. Veterinary journal. 203:120-125.

Christensen, L.L.; Selman, C.; Blount, J.D.; Pilkington, J.G.; Watt, K.; Pemberton, J.M.; Reid, J.M.; Nussey, D.H. (2015) Plasma markers of oxidative stress are uncorrelated in a wild mammal. Ecology & Evolution. 5:5096–5108.

Hayward, A.D.; Garnier, R.; Watt, K.A.; Pilkington, J.G.; Grenfell, B.T.; Matthews, J.B.; Pemberton, J.M.; Nussey, D.H.; Graham, A.L. (2014) Heritable, heterogeneous and costly resistance of sheep against nematodes and potential feedbacks to epidemiological dynamics American Naturalist. 184:S58-S76.

Hayward, A.D.; Nussey, D.H.; Wilson, A.J.; Berenos, C.; Pilkington, J.G.; Watt, K.A.; Pemberton, J.M.; Graham, A.L. (2014) Natural Selection on Individual Variation in Tolerance of Gastrointestinal Nematode Infection. PLoS Biology. 12:e1001917.

Nussey, D.H.; Watt, K.A.; Clark, A.; Pilkington, J.G.; Pemberton, J.M.; Graham, A.L.; McNeilly, T.N. (2104) Multivariate immune defences and fitness in the wild: Complex but ecologically important associations among plasma antibodies, health and survival. Proceedings of the Royal Society B-Biological Sciences. 281:20132931.

Brown E.A., Pilkington J.G., Nussey D.H., Watt K.A., Hayward A.D., Tucker R., Graham A.L., Paterson S., Beraldi D., Pemberton J.M. & Slate J. (2013). Detecting genes for variation in parasite burden and immunological traits in a wild population: testing the candidate gene approach. Molecular Ecology, 22: 757-773.

 
Nussey, D. H., Watt, K., Pilkington, J. G., Zamoyska, R. & McNeilly, T. N. 2012. Age-related variation in immunity in a wild mammal population. Aging Cell 11: 178-180.
 
Graham, A. L., Hayward, A. D., Watt, K. A., Pilkington, J. G., Pemberton, J. M. & Nussey, D. H. 2010. Fitness correlates of heritable variation in antibody responsiveness in a wild mammal. Science 330: 662-665.
 
Little, T. J., Chadwick, W. & Watt, K. 2008. Parasite variation and the evolution of virulence in a daphnia-microparasite system. Parasitology 135: 303-308.
 
Watt, K., Christofi, N. & Young, R. 2007. The detection of antibacterial actions of whole herb tinctures using luminescent escherichia coli. Phytotherapy Research 21: 1193-1199.
 
Grech, K., Watt, K. & Read, A. F. 2006. Host-parasite interactions for virulence and resistance in a malaria model system. Journal of Evolutionary Biology 19: 1620-1630.
 
Little, T. J., Watt, K. & Ebert, D. 2006. Parasite-host specificity: Experimental studies on the basis of parasite adaptation. Evolution 60: 31-38.
 
Little, T. J., O'Connor, B., Colegrave, N., Watt, K. & Read, A. F. 2003. Maternal transfer of strain-specific immunity in an invertebrate. Current Biology 13: 489-492.
 
Watt, D. M., Walker, A. R., Lamza, K. A. & Ambrose, N. C. 2001. Tick-theileria interactions in response to immune activation of the vector. Experimental Parasitology 97: 89-94.
 
Li, H., White, D., Lamza, K. A., Berger, F. & Leifert, C. 1998. Biological control of botrytis, phytophthora and pythium by bacillus subtilis cot1 and cl27 of micropropagated plants in high-humidity fogging glasshouses. Plant Cell Tissue and Organ Culture 52: 109-112.
 
Duncan, C., Li, H., Dykhuizen, R., Frazer, R., Johnston, P., MacKnight, G., Smith, L., Lamza, K., McKenzie, H., Batt, L., Kelly, D., Golden, M., Benjamin, N. & Leifert, C. 1997. Protection against oral and gastrointestinal diseases: Importance of dietary nitrate intake, oral nitrate reduction and enterosalivary nitrate circulation. Comparative Biochemistry and Physiology a-Molecular & Integrative Physiology 118: 939-948.
 
Li, H., White, D., Lamza, K. A., Berger, F. & Leifert, C. (1997) Biological control of botrytis, phytophthora and pythium by bacillus subtilis cot1 and cl27 of micropropagated plants in high-humidity fogging glasshouses. In: Pathogen and microbial contamination management in micropropagation, Vol. 12 (Cassells, A. C., ed.). pp. 339-344 Developments in plant pathology.
 
Taylor, D. M., Fraser, H., McConnell, I., Brown, D. A., Brown, K. L., Lamza, K. A. & Smith, G. R. A. 1994. Decontamination studies with the agents of bovine spongiform encephalopathy and scrapie. Archives of Virology 139: 313-326.